Transdiagnostic Brain Mapping in Developmental Disorders

DNA mapping in growth and developmental disorders.

DNA mapping techniques are being increasingly applied to familial and acquired disorders affecting growth and development. To understand the potential applications of these techniques, one must first have a good understanding of the components and basic structure of DNA, the genetic code, the basic structure of genes and the roles that various components of gene structure play in regulating gen...

BRAIN MAPPING IN NEUROSURGERY

Background and Aim: Brain mapping is a study of the anatomy and function of the CNS (central nervous system). Brain mapping has many techniques and these techniques are permanently changing and updating. From the beginning, brain mapping was invasive and for brain mapping, electrical stimulation of the exposed brain was needed. However, nowadays brain mapping does not require electrical stimula...

Brain mapping in Neurosurgical oncology

After the introduction of MRI, new modalities facilitated the procedure of surgical planning to achieve the microsurgical goal and improve prognosis and quality of life in patients. Despite the variable applications of preoperative and intraoperative mapping and monitoring systems, several limitations and concerns are reported for every modality as well. In this issue of the IrJNS, we are delig...

Oxidative stress in developmental brain disorders.

Oxidative stress is one of the predisposing factors in adult neurological disorders. We have examined the involvement of oxidative stress in child-onset neurodegenerative disorders, and here we review the findings from our analysis. In cases of Cockayne syndrome, the oxidative products of lipids and proteins were increased in the globus pallidus; however, oxidative nucleotide damage that coinci...

Brain Mapping of Developmental Coordination Disorder